CEO & President

Dr. Lockhart is an accomplished biotech executive with more than 25 years of experience across all phases of drug discovery, drug development and technology development.

Prior to joining ReCode Therapeutics (and its predecessor, TranscripTx) as CEO and President in 2014, he was the Chief Scientific Officer at Amicus Therapeutics from 2006 through 2013.  He led a team at Amicus that brought multiple programs into clinical trials of pharmacological chaperones used alone and in combination with enzyme replacement therapies for three different rare diseases.

Previously, he co-founded Ambit Biosciences, serving as Chief Scientific Officer and President for 5 years, during which the company developed a novel kinase profiling technology and new kinase inhibitors for cancer and other diseases.  Prior to Ambit, Dr. Lockhart served as Director of Genomics at the Genomics Institute of the Novartis Research Foundation (GNF).  Dr. Lockhart began his biotech career at Affymetrix, where he was the primary inventor and developer of gene expression profiling with DNA microarrays.

Dr. Lockhart received his Ph.D. in Chemistry from Stanford University and was a postdoctoral fellow at the Whitehead Institute in the Biology Department at MIT.  He has published more than 80 peer-reviewed scientific articles on pharmacological chaperones, mutation-specific selection of patients for clinical trials, clinical studies with pharmacological chaperones, genomics, kinase technology, kinase inhibitor discovery, and the use of genomic tools to address important biological and biomedical problems.  He is also the inventor on more than 40 issued U.S. patents.